Sulforaphane Promotes Dendritic Cell Stimulatory Capacity Through Modulation of Regulatory Molecules, JAK/STAT3- and MicroRNA-Signaling

INTRODUCTION: The broccoli isothiocyanate sulforaphane was shown to inhibit inflammation and tumor progression, also in pancreatic cancer, while its effect on tumor immunity is poorly understood. We investigated the immunoregulatory effect of sulforaphane on human dendritic cells alone and in presen...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Wang, Yangyi, Petrikova, Emilia, Gross, Wolfgang, Sticht, Carsten, Gretz, Norbert, Herr, Ingrid, Karakhanova, Svetlana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7661638/
https://ncbi.nlm.nih.gov/pubmed/33193420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.589818
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