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Novel Broccoli Sulforaphane-Based Analogues Inhibit the Progression of Pancreatic Cancer without Side Effects

The naturally occurring isothiocyanate sulforaphane, found in Brassicaceae vegetables, is promising in cancer treatment, e.g., by the normalization of enhanced levels of NF-κB-signaling in tumor stem cells. We chemically synthesized seven sulforaphane analogues by substitution of the sulfinyl group...

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Publicat a:Biomolecules
Autors principals: Georgikou, Christina, Buglioni, Laura, Bremerich, Maximilian, Roubicek, Nico, Yin, Libo, Gross, Wolfgang, Sticht, Carsten, Bolm, Carsten, Herr, Ingrid
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7277136/
https://ncbi.nlm.nih.gov/pubmed/32429039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10050769
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