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Novel Broccoli Sulforaphane-Based Analogues Inhibit the Progression of Pancreatic Cancer without Side Effects

The naturally occurring isothiocyanate sulforaphane, found in Brassicaceae vegetables, is promising in cancer treatment, e.g., by the normalization of enhanced levels of NF-κB-signaling in tumor stem cells. We chemically synthesized seven sulforaphane analogues by substitution of the sulfinyl group...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Georgikou, Christina, Buglioni, Laura, Bremerich, Maximilian, Roubicek, Nico, Yin, Libo, Gross, Wolfgang, Sticht, Carsten, Bolm, Carsten, Herr, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7277136/
https://ncbi.nlm.nih.gov/pubmed/32429039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10050769
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