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ICP6 Prevents RIP1 Activation to Hinder Necroptosis Signaling

Necroptosis is a type of programmed necrosis which depends on the activation of receptor-interacting protein kinase 3 (RIP3). Herpes simplex virus type 1 (HSV-1) is known to block necroptosis by the viral protein ICP6 in human cells, but its specific inhibitory mechanism is not fully understood. Her...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Hu, Hong, Wu, Guoxiang, Shu, Zhaoqian, Yu, Dandan, Nan, Ning, Yuan, Feiyang, Liu, Xiaoyan, Wang, Huayi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7661466/
https://ncbi.nlm.nih.gov/pubmed/33195272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.595253
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