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Highly Enantioselective Epoxidation of α,β-Unsaturated Ketones Using Amide-Based Cinchona Alkaloids as Hybrid Phase-Transfer Catalysts

[Image: see text] A series of 20 one chiral epoxides were obtained with excellent yields (up to 99%) and enantioselectivities (up to >99% ee) using hybrid amide-based Cinchona alkaloids. Our method is characterized by low catalyst loading (0.5 mol %) and short reaction times. Moreover, the epoxid...

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Bibliografiske detaljer
Udgivet i:Org Lett
Main Authors: Majdecki, Maciej, Tyszka-Gumkowska, Agata, Jurczak, Janusz
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660942/
https://ncbi.nlm.nih.gov/pubmed/33112627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c03272
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