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Inferring causal direction between two traits in the presence of horizontal pleiotropy with GWAS summary data

Orienting the causal relationship between pairs of traits is a fundamental task in scientific research with significant implications in practice, such as in prioritizing molecular targets and modifiable risk factors for developing therapeutic and interventional strategies for complex diseases. A rec...

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Bibliografiset tiedot
Julkaisussa:PLoS Genet
Päätekijät: Xue, Haoran, Pan, Wei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660933/
https://ncbi.nlm.nih.gov/pubmed/33137120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009105
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