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Role of Post-Translational Modifications of cGAS in Innate Immunity
Cyclic GMP–AMP synthase (cGAS) is the synthase that generates the second messenger cyclic GMP–AMP (cGAMP) upon DNA binding. cGAS was first discovered as the cytosolic DNA sensor that detects DNA exposed in the cytoplasm either from pathogens or cellular damage. Activated cGAS instigates the signalin...
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| Published in: | Int J Mol Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7660100/ https://ncbi.nlm.nih.gov/pubmed/33105828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21217842 |
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