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Molecular Regulation of the Polycomb Repressive-Deubiquitinase

Post-translational modification of histone proteins plays a major role in histone–DNA packaging and ultimately gene expression. Attachment of ubiquitin to the C-terminal tail of histone H2A (H2AK119Ub in mammals) is particularly relevant to the repression of gene transcription, and is removed by the...

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Foilsithe in:Int J Mol Sci
Main Authors: Reddington, Cameron J., Fellner, Matthias, Burgess, Abigail E., Mace, Peter D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660087/
https://ncbi.nlm.nih.gov/pubmed/33105797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21217837
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