Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids

Although congenital infection by human cytomegalovirus (HCMV) is well recognized as a leading cause of neurodevelopmental defects, HCMV neuropathogenesis remains poorly understood. A major challenge for investigating HCMV-induced abnormal brain development is the strict CMV species specificity, whic...

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Detalhes bibliográficos
Publicado no:Cell Rep Med
Main Authors: Sun, Guoqiang, Chiuppesi, Flavia, Chen, Xianwei, Wang, Cheng, Tian, E, Nguyen, Jenny, Kha, Mindy, Trinh, Daniel, Zhang, Hannah, Marchetto, Maria C., Song, Hongjun, Ming, Guo-Li, Gage, Fred H., Diamond, Don J., Wussow, Felix, Shi, Yanhong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659592/
https://ncbi.nlm.nih.gov/pubmed/33205055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2020.100002
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