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The Clinical Kinase Index: A Method to Prioritize Understudied Kinases as Drug Targets for the Treatment of Cancer

The approval of the first kinase inhibitor, Gleevec, ushered in a paradigm shift for oncological treatment—the use of genomic data for targeted, efficacious therapies. Since then, over 48 additional small-molecule kinase inhibitors have been approved, solidifying the case for kinases as a highly dru...

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Publicat a:Cell Rep Med
Autors principals: Essegian, Derek, Khurana, Rimpi, Stathias, Vasileios, Schürer, Stephan C.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659504/
https://ncbi.nlm.nih.gov/pubmed/33205077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2020.100128
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