Chimeric anti‐podoplanin antibody suppresses tumor metastasis through neutralization and antibody‐dependent cellular cytotoxicity

Podoplanin is a platelet aggregation‐inducing factor associated with tumor metastasis, malignant progression, and cancer stem cells. We produced a rat–human chimeric anti‐podoplanin mAb, NZ‐8, from rat anti‐podoplanin mAb (NZ‐1). Although both NZ‐1 and NZ‐8 possess high binding affinities and high n...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Kaneko, Mika Kato, Kunita, Akiko, Abe, Shinji, Tsujimoto, Yuta, Fukayama, Masashi, Goto, Kaoru, Sawa, Yoshihiko, Nishioka, Yasuhiko, Kato, Yukinari
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659283/
https://ncbi.nlm.nih.gov/pubmed/22816430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02385.x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados