Iron facilitator LS081 reduces hypoxia‐inducible factor‐1α protein and functions as anticancer agent in hepatocellular carcinoma

Hypoxia inducible factor‐1α (HIF‐1α) has a central role in cellular oxygen‐sensing, and its overexpression in many types of cancer is considered important in tumor progression. Thus, targeting HIF‐1α production and activity has been of great therapeutic interest. In normoxic conditions, HIF‐1α is hy...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Tanaka, Hiroki, Li, Zhen, Ikuta, Katsuya, Addo, Lynda, Akutsu, Hiroaki, Nakamura, Masao, Sasaki, Katsunori, Ohtake, Takaaki, Fujiya, Mikihiro, Torimoto, Yoshihiro, Glass, Jonathan, Kohgo, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659231/
https://ncbi.nlm.nih.gov/pubmed/22181812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2011.02192.x
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