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Combination of ADH1B*2/ALDH2*2 polymorphisms alters acetaldehyde‐derived DNA damage in the blood of Japanese alcoholics

The acetaldehyde associated with alcoholic beverages is an evident carcinogen for the esophagus. Genetic polymorphisms of the alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2) genes are associated with the risk of esophageal cancer. However, the exact mechanism via which these ge...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Yukawa, Yoshiyuki, Muto, Manabu, Hori, Kimiko, Nagayoshi, Haruna, Yokoyama, Akira, Chiba, Tsutomu, Matsuda, Tomonari
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659228/
https://ncbi.nlm.nih.gov/pubmed/22703580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02360.x
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