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Combination of ADH1B*2/ALDH2*2 polymorphisms alters acetaldehyde‐derived DNA damage in the blood of Japanese alcoholics

The acetaldehyde associated with alcoholic beverages is an evident carcinogen for the esophagus. Genetic polymorphisms of the alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2) genes are associated with the risk of esophageal cancer. However, the exact mechanism via which these ge...

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Bibliografski detalji
Izdano u:Cancer Sci
Glavni autori: Yukawa, Yoshiyuki, Muto, Manabu, Hori, Kimiko, Nagayoshi, Haruna, Yokoyama, Akira, Chiba, Tsutomu, Matsuda, Tomonari
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659228/
https://ncbi.nlm.nih.gov/pubmed/22703580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02360.x
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