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Development of an early induction model of medulloblastoma in Ptch1 heterozygous mice initiated with N‐ethyl‐N‐nitrosourea

Mice heterozygous for the ptch1 gene (ptch1 mice) are known as a valuable model of medulloblastoma, a common brain tumor in children. To increase the incidence and reduce the time required for tumor development, allowing for evaluation of modifier effects on medulloblastoma in a short time, we attem...

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Vydáno v:Cancer Sci
Hlavní autoři: Takahashi, Miwa, Matsuo, Saori, Inoue, Kaoru, Tamura, Kei, Irie, Kaoru, Kodama, Yukio, Yoshida, Midori
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659221/
https://ncbi.nlm.nih.gov/pubmed/22937732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12006
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