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Magnetic resonance tumor targeting imaging using gadolinium labeled human telomerase reverse transcriptase antisense probes

To develop a molecular probe for MRI detection of human tumor telomerase reverse transcriptase (hTERT) mRNA expression. Uniformly phosphorothioate‐modified hTERT antisense oligonucleotide (ASON) homing hTERT mRNA was labeled with gadolinium (Gd) through the bifunctional chelator 1,4,7, 10‐tetraazacy...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Ren, Bing Xiu, Yang, Fan, Zhu, Gao Hong, Huang, Zi Xing, Ai, Hua, Xia, Rui, Liu, Xi Jiao, Lu, Man, Song, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659201/
https://ncbi.nlm.nih.gov/pubmed/22534012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02316.x
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