Hypoxia induces gefitinib resistance in non‐small‐cell lung cancer with both mutant and wild‐type epidermal growth factor receptors

Somatic mutations in the epidermal growth factor receptor (EGFR) gene, such as exon 19 deletion mutations, are important factors in determining therapeutic responses to gefitinib in non‐small‐cell lung cancer (NSCLC). However, some patients have activating mutations in EGFR and show poor responses t...

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Vydáno v:Cancer Sci
Hlavní autoři: Minakata, Kunihiko, Takahashi, Fumiyuki, Nara, Takeshi, Hashimoto, Muneaki, Tajima, Ken, Murakami, Akiko, Nurwidya, Fariz, Yae, Suzu, Koizumi, Fumiaki, Moriyama, Hiroyuki, Seyama, Kuniaki, Nishio, Kazuto, Takahashi, Kazuhisa
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2012
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659171/
https://ncbi.nlm.nih.gov/pubmed/22863020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02408.x
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