Hypoxia induces gefitinib resistance in non‐small‐cell lung cancer with both mutant and wild‐type epidermal growth factor receptors

Somatic mutations in the epidermal growth factor receptor (EGFR) gene, such as exon 19 deletion mutations, are important factors in determining therapeutic responses to gefitinib in non‐small‐cell lung cancer (NSCLC). However, some patients have activating mutations in EGFR and show poor responses t...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Minakata, Kunihiko, Takahashi, Fumiyuki, Nara, Takeshi, Hashimoto, Muneaki, Tajima, Ken, Murakami, Akiko, Nurwidya, Fariz, Yae, Suzu, Koizumi, Fumiaki, Moriyama, Hiroyuki, Seyama, Kuniaki, Nishio, Kazuto, Takahashi, Kazuhisa
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2012
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659171/
https://ncbi.nlm.nih.gov/pubmed/22863020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02408.x
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