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Oxidative stress induced by the anti-cancer agents, plumbagin, and atovaquone, inhibits ion transport through Na(+)/K(+)-ATPase
Oxidative stress inhibits Na(+)/K(+)-ATPase (NKA), the ion channel that maintains membrane potential. Here, we investigate the role of oxidative stress-mediated by plumbagin and atovaquone in the inhibition of NKA activity. We confirm that plumbagin and atovaquone inhibit the proliferation of three...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7659016/ https://ncbi.nlm.nih.gov/pubmed/33177587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76342-5 |
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