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Plumbagin-induced oxidative stress leads to inhibition of Na(+)/K(+)-ATPase (NKA) in canine cancer cells
The Na(+)/K(+)-ATPase (NKA) complex is the master regulator of membrane potential and a target for anti-cancer therapies. Here, we investigate the effect of drug-induced oxidative stress on NKA activity. The natural product, plumbagin increases oxygen radicals through inhibition of oxidative phospho...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6685937/ https://ncbi.nlm.nih.gov/pubmed/31391478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47261-x |
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