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Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders: A Multivariable Mendelian Randomization Analysis

IMPORTANCE: Growing evidence suggests that prescription opioid use affects depression and anxiety disorders; however, observational studies are subject to confounding, making causal inference and determining the direction of these associations difficult. OBJECTIVE: To investigate the potential bidir...

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Pubblicato in:JAMA Psychiatry
Autori principali: Rosoff, Daniel B., Smith, George Davey, Lohoff, Falk W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658804/
https://ncbi.nlm.nih.gov/pubmed/33175090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2020.3554
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