The Synovium Attenuates Cartilage Degeneration in KOA through Activation of the Smad2/3-Runx1 Cascade and Chondrogenesis-related miRNAs

Knee osteoarthritis (KOA) is a highly prevalent disabling joint disease in aged people. Progressive cartilage degradation is the hallmark of KOA, but its deeper mechanism remains unclear. Substantial evidence indicates the importance of the synovium for joint homeostasis. The present study aimed to...

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Bibliografiska uppgifter
I publikationen:Mol Ther Nucleic Acids
Huvudupphovsmän: Zhao, Xiaoyi, Meng, Fangang, Hu, Shu, Yang, Zibo, Huang, Hao, Pang, Rui, Wen, Xingzhao, Kang, Yan, Zhang, Zhiqi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Gene & Cell Therapy 2020
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658376/
https://ncbi.nlm.nih.gov/pubmed/33230479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.10.004
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