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The Synovium Attenuates Cartilage Degeneration in KOA through Activation of the Smad2/3-Runx1 Cascade and Chondrogenesis-related miRNAs

Knee osteoarthritis (KOA) is a highly prevalent disabling joint disease in aged people. Progressive cartilage degradation is the hallmark of KOA, but its deeper mechanism remains unclear. Substantial evidence indicates the importance of the synovium for joint homeostasis. The present study aimed to...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Zhao, Xiaoyi, Meng, Fangang, Hu, Shu, Yang, Zibo, Huang, Hao, Pang, Rui, Wen, Xingzhao, Kang, Yan, Zhang, Zhiqi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658376/
https://ncbi.nlm.nih.gov/pubmed/33230479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.10.004
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