Natural Killer Lytic-Associated Molecule (NKLAM): An E3 Ubiquitin Ligase With an Integral Role in Innate Immunity

Natural Killer Lytic-Associated Molecule (NKLAM), also designated RNF19B, is a unique member of a small family of E3 ubiquitin ligases. This 14-member group of ligases has a characteristic cysteine-rich RING-IBR-RING (RBR) domain that mediates the ubiquitination of multiple substrates. The consequen...

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Vydáno v:Front Physiol
Hlavní autoři: Lawrence, Donald W., Willard, Paul A., Cochran, Allyson M., Matchett, Emily C., Kornbluth, Jacki
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658342/
https://ncbi.nlm.nih.gov/pubmed/33192571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.573372
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