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Natural killer lytic-associated molecule plays a role in controlling tumor dissemination and metastasis

Natural killer lytic-associated molecule (NKLAM) is an E3 ubiquitin ligase that plays a major role in the cytolytic activity of NK cells. NKLAM is rapidly synthesized and then targeted to the granule membranes of NK cells upon NK activation. Previous studies have shown an essential role for NKLAM in...

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Detalhes bibliográficos
Main Authors: Hoover, Richard G., Gullickson, Gail, Kornbluth, Jacki
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529306/
https://ncbi.nlm.nih.gov/pubmed/23269922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00393
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