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A steric gate controls P/E hybrid-state formation of tRNA on the ribosome

The ribosome is a biomolecular machine that undergoes multiple large-scale structural rearrangements during protein elongation. Here, we focus on a conformational rearrangement during translocation, known as P/E hybrid-state formation. Using a model that explicitly represents all non-hydrogen atoms,...

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Udgivet i:Nat Commun
Main Authors: Levi, Mariana, Walak, Kelsey, Wang, Ailun, Mohanty, Udayan, Whitford, Paul C.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658246/
https://ncbi.nlm.nih.gov/pubmed/33177497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19450-0
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