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Steric interactions lead to collective tilting motion in the ribosome during mRNA–tRNA translocation
Translocation of mRNA and tRNA through the ribosome is associated with large-scale rearrangements of the head domain in the 30S ribosomal subunit. To elucidate the relationship between 30S head dynamics and mRNA–tRNA displacement, we apply molecular dynamics simulations using an all-atom structure-b...
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| 發表在: | Nat Commun |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4742886/ https://ncbi.nlm.nih.gov/pubmed/26838673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10586 |
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