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Structural basis for mRNA and tRNA positioning on the ribosome

Protein synthesis requires the accurate positioning of mRNA and tRNA in the peptidyl-tRNA site of the ribosome. Here we describe x-ray crystal structures of the intact bacterial ribosome from Escherichia coli in a complex with mRNA and the anticodon stem-loop of P-site tRNA. At 3.5-Å resolution, the...

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Autors principals: Berk, Veysel, Zhang, Wen, Pai, Raj D., Cate, Jamie H. D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635088/
https://ncbi.nlm.nih.gov/pubmed/17038497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607541103
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