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EZH2 inhibition reduces cartilage loss and functional impairment related to osteoarthritis
Histone methyltransferase EZH2 is upregulated during osteoarthritis (OA), which is the most widespread rheumatic disease worldwide, and a leading cause of disability. This study aimed to assess the impact of EZH2 inhibition on cartilage degradation, inflammation and functional disability. In vitro,...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7658239/ https://ncbi.nlm.nih.gov/pubmed/33177650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76724-9 |
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