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A novel Trypanosoma cruzi secreted antigen as a potential biomarker of Chagas disease

Chagas drug discovery has been hampered by a lack of validated assays to establish treatment efficacy in pre-clinical animal models and in patients infected with T. cruzi. Reduced levels of parasite secreted antigens in the blood of infected hosts could be used to demonstrate treatment efficacy. A p...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Nagarkatti, Rana, Acosta, David, Acharyya, Nirmallya, de Araujo, Fernanda Fortes, Elói-Santos, Silvana Maria, Martins-Filho, Olindo Assis, Teixeira-Carvalho, Andréa, Debrabant, Alain
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658208/
https://ncbi.nlm.nih.gov/pubmed/33177582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76508-1
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