Blood leukocytes from benznidazole-treated indeterminate chagas disease patients display an overall type-1-modulated cytokine profile upon short-term in vitro stimulation with trypanosoma cruzi antigens

BACKGROUND: Benznidazole (Bz)-chemotherapy is recommended to prevent Chagas disease progression, despite its limited efficacy during chronic disease. However, the host mechanisms underlying these benefits still remain to be elucidated. METHODS: In this study, we have used short-term whole blood cult...

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Hauptverfasser: Sathler-Avelar, Renato, Vitelli-Avelar, Danielle Marquete, Elói-Santos, Silvana Maria, Gontijo, Eliane Dias, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3519593/
https://ncbi.nlm.nih.gov/pubmed/22625224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-12-123
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