Upstream development of Escherichia coli fermentation process with PhoA promoter using design of experiments (DoE)

In this work, a fed-batch fermentation development was performed with recombinant E. coli carrying the PhoA promoter system. The phosphate concentrations tested for this PhoA strain, 2.79 mM to 86.4 mM, were beyond the concentrations previously evaluated for cell growth and product titer. The result...

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Библиографические подробности
Опубликовано в: :J Ind Microbiol Biotechnol
Главные авторы: Agbogbo, Frank K., Ramsey, Phil, George, Renija, Joy, Jobin, Srivastava, Shikha, Huang, Mian, McCool, Jesse
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing 2020
Предметы:
Fermentation, Cell Culture and Bioengineering - Original Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658055/
https://ncbi.nlm.nih.gov/pubmed/32844325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-020-02302-7
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