Notch regulates innate lymphoid cell plasticity during human natural killer cell development

Human natural killer (NK) cells develop in tonsils through discrete NK cell developmental intermediates (NKDIs), yet the mechanistic regulation of this process is unclear. We demonstrate that Notch activation in human tonsil-derived stage 3 (CD34(−)CD117(+)CD94(−)NKp80(−)) and 4A (CD34(−)CD117(+/−)C...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Nalin, Ansel P., Kowalski, Jesse J., Sprague, Alexander C., Schumacher, Blaire K., Gerhardt, Adam G., Youssef, Youssef, Vedantam, Kiran V., Zhang, Xiaoli, Siebel, Christian W., Mace, Emily M., Caligiuri, Michael A., Mundy-Bosse, Bethany L., Freud, Aharon G.
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7658047/
https://ncbi.nlm.nih.gov/pubmed/33020148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000434
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