Incorporating Multiple Sets of eQTL Weights into Gene-by-Environment Interaction Analysis Identifies Novel Susceptibility Loci for Pancreatic Cancer

It is of great scientific interest to identify interactions between genetic variants and environmental exposures that may modify the risk of complex diseases. However, larger sample sizes are usually required to detect gene-by-environment interaction (GxE) than required to detect genetic main associ...

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Vydáno v:Genet Epidemiol
Hlavní autoři: Yang, Tianzhong, Tang, Hongwei, Risch, Harvey A., Olson, Sara H., Petersen, Gloria, Bracci, Paige M., Gallinger, Steven, Hung, Rayjean, Neale, Rachel E., Scelo, Ghislaine, Duell, Eric J., Kurtz, Robert C., Khaw, Kay-Tee, Severi, Gianluca, Sund, Malin, Wareham, Nick, Amos, Christopher I, Li, Donghui, Wei, Peng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657998/
https://ncbi.nlm.nih.gov/pubmed/32779232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22348
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