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Treg cells maintain selective access to IL-2 and immune homeostasis despite substantially reduced CD25 function

Interleukin-2 (IL-2) is a critical regulator of immune homeostasis through its impact on both regulatory T (Treg) and effector T (Teff) cells. However, the precise role of IL-2 in the maintenance and function of Treg cells in the adult peripheral immune system remains unclear. Here, we report that n...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Hayes, Erika T., Hagan, Cassidy E., Khoryati, Liliane, Gavin, Marc, Campbell, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657993/
https://ncbi.nlm.nih.gov/pubmed/33055282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901520
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