Site-Specific Radioiodination of an Anti-HER2 Single Domain Antibody Fragment with a Residualizing Prosthetic Agent

INTRODUCTION: As a consequence of their small size, high stability and high affinity, single domain antibody fragments (sdAb) are appealing targeting vectors for radiopharmaceutical development. With sdAbs binding to internalizing receptors like HER2, residualizing prosthetic agents can enhance tumo...

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Vydáno v:Nucl Med Biol
Hlavní autoři: Feng, Yutian, Zhou, Zhengyuan, McDougald, Darryl, Meshaw, Rebecca L., Vaidyanathan, Ganesan, Zalutsky, Michael R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657985/
https://ncbi.nlm.nih.gov/pubmed/32448731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2020.05.002
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