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TNFα Regulates Intestinal Organoids from Mice with Both Defined and Conventional Microbiota

Cytokines are key factors affecting the fate of intestinal stem cells (ISCs) and effective reagents to manipulate ISCs for research purpose. Tumor necrosis factor alpha (TNFα) is a cytokine produced primarily by monocytes and macrophages. It can induce apoptotic cell death and inflammation, and to i...

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Detalhes bibliográficos
Publicado no:Int J Biol Macromol
Main Authors: Sun, Liping, Rollins, Derrick, Qi, Yijun, Fredericks, Jorrell, Mansell, Thomas J., Jergens, Albert, Phillips, Gregory J, Wannemuehler, Michael, Wang, Qun
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657954/
https://ncbi.nlm.nih.gov/pubmed/32693143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijbiomac.2020.07.176
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