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Gut Organoid as a New Platform to Study Alginate and Chitosan Mediated PLGA Nanoparticles for Drug Delivery

Intestinal organoids can be used as an ex vivo epithelial model to study different drug delivery effects on epithelial cells’ luminal surface. In this study, the impact of surface charge on the delivery of 5-ASA loaded PLGA nanoparticles into the lumen of organoids was investigated. Alginate and chi...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Davoudi, Zahra, Peroutka-Bigus, Nathan, Bellaire, Bryan, Jergens, Albert, Wannemuehler, Michael, Wang, Qun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161322/
https://ncbi.nlm.nih.gov/pubmed/34065505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md19050282
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