Reduced Chronic Toxicity and Carcinogenicity in A/J Mice in Response to Life-Time Exposure to Aerosol From a Heated Tobacco Product Compared With Cigarette Smoke

We conducted an inhalation study, in accordance with Organisation for Economic Co-operation and Development Test Guideline 453, exposing A/J mice to tobacco heating system (THS) 2.2 aerosol or 3R4F reference cigarette smoke (CS) for up to 18 months to evaluate chronic toxicity and carcinogenicity. A...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Wong, Ee Tsin, Luettich, Karsta, Krishnan, Subash, Wong, Sin Kei, Lim, Wei Ting, Yeo, Demetrius, Büttner, Ansgar, Leroy, Patrice, Vuillaume, Grégory, Boué, Stéphanie, Hoeng, Julia, Vanscheeuwijck, Patrick, Peitsch, Manuel C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657344/
https://ncbi.nlm.nih.gov/pubmed/32780830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa131
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