5-aminoimidazole-4-carboxamide ribonucleoside induces differentiation in a subset of primary acute myeloid leukemia blasts

BACKGROUND: All-trans retinoic acid (ATRA)-based treatment of acute promyelocytic leukemia (APL) is the most successful pharmacological treatment of acute myeloid leukemia (AML). Recent development of inhibitors of mutated isocitrate dehydrogenase and dihydroorotate dehydrogenase (DHODH) has revived...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:BMC Cancer
Hoofdauteurs: Dembitz, Vilma, Lalic, Hrvoje, Kodvanj, Ivan, Tomic, Barbara, Batinic, Josip, Dubravcic, Klara, Batinic, Drago, Bedalov, Antonio, Visnjic, Dora
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657321/
https://ncbi.nlm.nih.gov/pubmed/33176741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07533-6
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items