Klotho suppresses tumor progression via inhibiting PI3K/Akt/GSK3β/Snail signaling in renal cell carcinoma

Klotho is an anti‐aging protein predominantly expressed in renal tubular epithelial cells. Although Klotho was recently identified as a tumor suppressor gene in a variety of cancers, the potential role and molecular events for Klotho in renal cell carcinoma (RCC) remain obscure. In the present study...

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Vydáno v:Cancer Sci
Hlavní autoři: Zhu, Yu, Xu, Le, Zhang, Jianping, Xu, Wenping, Liu, Yujun, Yin, Hankun, Lv, Tao, An, Huimin, Liu, Li, He, Hongyong, Zhang, Heng, Liu, Jing, Xu, Jiejie, Lin, Zongming
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2013
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7657207/
https://ncbi.nlm.nih.gov/pubmed/23433103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12134
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