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Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer

BACKGROUND: Immunogenic cell death (ICD) is a tumor cell death involving both innate and adaptive immune responses. Given published findings that oxaliplatin, but not irinotecan, drives ICD, we investigated whether single nucleotide polymorphisms (SNPs) in the ICD pathway are associated with the eff...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Arai, Hiroyuki, Xiao, Yi, Loupakis, Fotios, Kawanishi, Natsuko, Wang, Jingyuan, Battaglin, Francesca, Soni, Shivani, Zhang, Wu, Mancao, Christoph, Salhia, Bodour, Mumenthaler, Shannon M, Weisenberger, Daniel J, Liang, Gangning, Cremolini, Chiara, Falcone, Alfredo, Millstein, Joshua, Lenz, Heinz-Josef
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656952/
https://ncbi.nlm.nih.gov/pubmed/33172883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001714
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