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Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer

BACKGROUND: Immunogenic cell death (ICD) is a tumor cell death involving both innate and adaptive immune responses. Given published findings that oxaliplatin, but not irinotecan, drives ICD, we investigated whether single nucleotide polymorphisms (SNPs) in the ICD pathway are associated with the eff...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Immunother Cancer
Main Authors: Arai, Hiroyuki, Xiao, Yi, Loupakis, Fotios, Kawanishi, Natsuko, Wang, Jingyuan, Battaglin, Francesca, Soni, Shivani, Zhang, Wu, Mancao, Christoph, Salhia, Bodour, Mumenthaler, Shannon M, Weisenberger, Daniel J, Liang, Gangning, Cremolini, Chiara, Falcone, Alfredo, Millstein, Joshua, Lenz, Heinz-Josef
פורמט: Artigo
שפה:Inglês
יצא לאור: BMJ Publishing Group 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656952/
https://ncbi.nlm.nih.gov/pubmed/33172883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001714
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