Whole transcriptome sequencing detects a large number of novel fusion transcripts in patients with AML and MDS

Fusion transcripts are frequent genetic abnormalities in myeloid malignancies and are often the basis for risk stratification, minimal residual disease (MRD) monitoring, and targeted therapy. We comprehensively analyzed the fusion transcript landscape in 572 acute myeloid leukemia (AML) and 630 myel...

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Veröffentlicht in:Blood Adv
Hauptverfasser: Stengel, Anna, Shahswar, Rabia, Haferlach, Torsten, Walter, Wencke, Hutter, Stephan, Meggendorfer, Manja, Kern, Wolfgang, Haferlach, Claudia
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2020
Schlagworte:
Myeloid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656918/
https://ncbi.nlm.nih.gov/pubmed/33147338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003007
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