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Whole transcriptome sequencing detects a large number of novel fusion transcripts in patients with AML and MDS

Fusion transcripts are frequent genetic abnormalities in myeloid malignancies and are often the basis for risk stratification, minimal residual disease (MRD) monitoring, and targeted therapy. We comprehensively analyzed the fusion transcript landscape in 572 acute myeloid leukemia (AML) and 630 myel...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Stengel, Anna, Shahswar, Rabia, Haferlach, Torsten, Walter, Wencke, Hutter, Stephan, Meggendorfer, Manja, Kern, Wolfgang, Haferlach, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656918/
https://ncbi.nlm.nih.gov/pubmed/33147338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003007
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