Outcome of patients with IDH1/2-mutated post–myeloproliferative neoplasm AML in the era of IDH inhibitors

IDH1/2-inhibitor–based combinations conferred significant clinical responses in patients with IDH1/2-mutated post–MPN AML. Complete remission was achieved in 3/7 patients (1 attaining MRD–) with new IDH1/2-mutated post–MPN AML treated with IDH1/2-i combinations.

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Bibliographische Detailangaben
Veröffentlicht in:Blood Adv
Hauptverfasser: Chifotides, Helen T., Masarova, Lucia, Alfayez, Mansour, Daver, Naval, Alvarado, Yesid, Jabbour, Elias, Konopleva, Marina, Kantarjian, Hagop M., Patel, Keyur P., DiNardo, Courtney D., Verstovsek, Srdan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2020
Schlagworte:
Stimulus Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656917/
https://ncbi.nlm.nih.gov/pubmed/33112940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001528
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