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Pinocembrin ameliorates intermittent hypoxia-induced neuroinflammation through BNIP3-dependent mitophagy in a murine model of sleep apnea

BACKGROUND: Intermittent hypoxia (IH) caused by obstructive sleep apnea (OSA) leads to neuroinflammation. Pinocembrin has been shown to have neuroprotective effects, while the therapeutic functions under IH condition are still unknown. METHODS: An OSA model was established by CIH exposure inside cus...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Gong, Lin-Jing, Wang, Xin-Yuan, Gu, Wen-Yu, Wu, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656728/
https://ncbi.nlm.nih.gov/pubmed/33176803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-02014-w
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