Pinocembrin ameliorates intermittent hypoxia-induced neuroinflammation through BNIP3-dependent mitophagy in a murine model of sleep apnea

BACKGROUND: Intermittent hypoxia (IH) caused by obstructive sleep apnea (OSA) leads to neuroinflammation. Pinocembrin has been shown to have neuroprotective effects, while the therapeutic functions under IH condition are still unknown. METHODS: An OSA model was established by CIH exposure inside cus...

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Publié dans:J Neuroinflammation
Auteurs principaux: Gong, Lin-Jing, Wang, Xin-Yuan, Gu, Wen-Yu, Wu, Xu
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656728/
https://ncbi.nlm.nih.gov/pubmed/33176803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-02014-w
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