Impact of the common MTHFR 677C→T polymorphism on blood pressure in adulthood and role of riboflavin in modifying the genetic risk of hypertension: evidence from the JINGO project

BACKGROUND: Genome-wide and clinical studies have linked the 677C→T polymorphism in the gene encoding methylenetetrahydrofolate reductase (MTHFR) with hypertension, whilst limited evidence shows that intervention with riboflavin (i.e. the MTHFR co-factor) can lower blood pressure (BP) in hypertensiv...

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Détails bibliographiques
Publié dans:BMC Med
Auteurs principaux: Ward, Mary, Hughes, Catherine F., Strain, J. J., Reilly, Rosie, Cunningham, Conal, Molloy, Anne M., Horigan, Geraldine, Casey, Miriam, McCarroll, Kevin, O’Kane, Maurice, Gibney, Michael J., Flynn, Albert, Walton, Janette, McNulty, Breige A., McCann, Adrian, Kirwan, Laura, Scott, John M., McNulty, Helene
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656675/
https://ncbi.nlm.nih.gov/pubmed/33172445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-020-01780-x
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