Impact of the common MTHFR 677C→T polymorphism on blood pressure in adulthood and role of riboflavin in modifying the genetic risk of hypertension: evidence from the JINGO project

BACKGROUND: Genome-wide and clinical studies have linked the 677C→T polymorphism in the gene encoding methylenetetrahydrofolate reductase (MTHFR) with hypertension, whilst limited evidence shows that intervention with riboflavin (i.e. the MTHFR co-factor) can lower blood pressure (BP) in hypertensiv...

詳細記述

保存先:
書誌詳細
出版年:BMC Med
主要な著者: Ward, Mary, Hughes, Catherine F., Strain, J. J., Reilly, Rosie, Cunningham, Conal, Molloy, Anne M., Horigan, Geraldine, Casey, Miriam, McCarroll, Kevin, O’Kane, Maurice, Gibney, Michael J., Flynn, Albert, Walton, Janette, McNulty, Breige A., McCann, Adrian, Kirwan, Laura, Scott, John M., McNulty, Helene
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656675/
https://ncbi.nlm.nih.gov/pubmed/33172445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-020-01780-x
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