Evidence that cannabinoid CB1 receptors regulate intraocular pressure via two opposing mechanisms

The cannabinoid signaling system regulates intraocular pressure (IOP) in the mouse via a complex system that includes three receptors: CB1, GPR18 and GPR119. In each case, activating the receptor lowers IOP, but CB1 receptors are found both at sites of aqueous humor inflow and outflow. As such, knoc...

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Bibliographic Details
Published in:Exp Eye Res
Main Authors: Miller, Sally, Daily, Laura, Ploss, Maya, Greig, Iain, Ross, Ruth, Rayana, Naga Pradeep, Dai, Jiannong, Sugali, Chenna Kesavulu, Mao, Weiming, Straiker, Alex
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655705/
https://ncbi.nlm.nih.gov/pubmed/32941875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2020.108241
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