Role of androgen receptor splice variant 7 (AR-V7) in prostate cancer resistance to 2(nd) generation androgen receptor signaling inhibitors

The role of truncated androgen receptor splice variant-7 (AR-V7) in prostate cancer biology is an unresolved question. Is it simply a marker of resistance to 2(nd) generation androgen receptor signaling inhibitors (ARSi) like Abiraterone Acetate (Abi) and Enzalutamide (Enza) or a functional driver o...

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Udgivet i:Oncogene
Main Authors: Zhu, Yezi, Dalrymple, Susan L., Coleman, Ilsa, Zheng, S. Lilly, Xu, Jianfeng, Hooper, Jody E., Antonarakis, Emmanuel S., De Marzo, Angelo M., Meeker, Alan K., Nelson, Peter S., Isaacs, William B., Denmeade, Samuel R., Luo, Jun, Brennen, W. Nathaniel, Isaacs, John T.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655549/
https://ncbi.nlm.nih.gov/pubmed/32989253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01479-6
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