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Interleukin-6 knockout reverses macrophage differentiation imbalance and alleviates cardiac dysfunction in aging mice

Several interleukins (ILs) have been shown to be involved in aging, but the effects of IL-6 on aging-related cardiac dysfunction remain unknown. In this study, the expression and sources of cardiac IL-6 in aging hearts were investigated for the first time. The results showed that cardiac IL-6 expres...

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Publicado en:Aging (Albany NY)
Autores principales: Wang, Yuan, Zhu, Shan, Wei, Wen, Tu, Yi, Chen, Chuang, Song, Junlong, Li, Juanjuan, Wang, Changhua, Xu, Zhiliang, Sun, Shengrong
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655174/
https://ncbi.nlm.nih.gov/pubmed/33099539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103749
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