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Hippocampal and cortical tissue-specific epigenetic clocks indicate an increased epigenetic age in a mouse model for Alzheimer’s disease

Epigenetic clocks are based on age-associated changes in DNA methylation of CpG-sites, which can accurately measure chronological age in different species. Recently, several studies have indicated that the difference between chronological and epigenetic age, defined as the age acceleration, could re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Coninx, Emma, Chew, Yap Ching, Yang, Xiaojing, Guo, Wei, Coolkens, Amelie, Baatout, Sarah, Moons, Lieve, Verslegers, Mieke, Quintens, Roel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655172/
https://ncbi.nlm.nih.gov/pubmed/33082299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.104056
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