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Exposure to Ionizing Radiation Triggers Prolonged Changes in Circular RNA Abundance in the Embryonic Mouse Brain and Primary Neurons

The exposure of mouse embryos in utero and primary cortical neurons to ionizing radiation results in the P53-dependent activation of a subset of genes that is highly induced during brain development and neuronal maturation, a feature that these genes reportedly share with circular RNAs (circRNAs). I...

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Publicado en:Cells
Autores principales: Mbouombouo Mfossa, André Claude, Thekkekara Puthenparampil, Helene, Inalegwu, Auchi, Coolkens, Amelie, Baatout, Sarah, Benotmane, Mohammed A., Huylebroeck, Danny, Quintens, Roel
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721538/
https://ncbi.nlm.nih.gov/pubmed/31357500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080778
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